Fluorescence tomographic reconstruction can be used to reveal the internal elemental composition of a sample. On the other hand, transmission tomography can be used to obtain the spatial distribution of the absorption coefficient inside the sample. In this work, we integrate both modalities and formulate an optimization approach to simultaneously reconstruct the composition and absorption effect in the sample. The result is demonstrated on a simple sample. As the second part of this talk, I will discuss the image registration problems and some explorations on a MATLAB-based package called 'FAIR' which can be used for solving the correspondence problem.