Understanding the effects of drugs on the brain: A look at the damage and potential for treatment

Neuron Image

A connectomic analysis of the brains of mice treated with cocaine shows that dopamine axons undergo two major anatomical remodeling events: 1) axons increase the average number of branches they make (top image), 2) while simultaneously pruning, or removing, existing axons. (Image by Gregg Wildenberg, University of Chicago/Argonne National Laboratory.)