We are inviting submissions for a proposal for a new program fast-tracking novel AI applications in science. Projects should apply AI creatively, require leadership-scale computing, and integrate training, inference, simulation, and analytics. Selected teams receive compute allocations, expert collaborators, and an ALCF-funded postdoctoral researcher. New and existing users welcome. Proposals are due February 27, 2026. For more information, visit: https://www.alcf.anl.gov/science/apex