2025 ALCF Science Report Report Explore the ALCF’s 2025 Science Report to learn how our user community is breaking new ground in scientific computing. From AI-driven advances in biomedicine and materials discovery to high-fidelity simulations of hypersonic flight and rapid data analysis for experiments, ALCF’s HPC and AI resources are enabling high-impact research at unprecedented scale and speed. Energy department launches Genesis Mission AI for Science Argonne will play a pivotal role in the national effort to harness AI for breakthroughs in scientific discovery, energy innovation, and national security. Aurora News Aurora Science and User News Argonne’s Aurora Supercomputer Enables Trillion-Atom Light–Matter Simulations HPCwire Building AI Foundation Models to Accelerate the Discovery of New Battery Materials HPCwire US supercomputers train on billions of molecules to boost battery material discovery Interesting Engineering Foundation Models to Accelerate the Discovery of New Battery Materials CleanTechnica Learn More About Aurora Argonne researchers and supercomputers contribute to four Gordon Bell Prize finalists Science DOE's exascale systems, including ALCF's Aurora, power groundbreaking studies in AI-driven weather forecasting, cosmology, light-matter dynamics, and quantum materials research. Argonne hosts Intro to HPC Bootcamp to train next-gen computational scientists Outreach Bringing together participants from a range of science disciplines, the Argonne Intro to HPC Bootcamp focuses on foundational concepts in high-performance computing to help participants apply them to projects focused on real-world challenges. Deploying Inference Services at ALCF Webinar Join us on Wednesday, December 3, 2025, for a webinar showcasing the ALCF's Inference Service, which provides cloud-like access to diverse AI models—including large language models (LLMs)—on existing HPC clusters Argonne’s GridFTP Innovation wins SC25 Test of Time Award Award A landmark paper from Argonne scientists, including ALCF's Bill Allcock, is being recognized for transforming how massive datasets move across supercomputing systems.